24 results
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
hemangiomata, clubbing ... capillary leak syndrome ... Hypergammaglobulinemic macular ... (Thrombosis in vascular ... Differential #Diagnosis #Oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Cathepsin G release → vascular ... Diagnosis: >3 symptoms ... management #hematology #oncology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... seated position, or climbing ... Guillain-Barré syndrome ... antisynthetase syndrome ... after DC Statin Treatment
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... There are several symptoms ... (shown in the video ... elevation in the muscular
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Episcleritis Signs and Symptoms ... development of skin symptoms ... Treatment: - Systemic ... #dermatology #oncology
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Wheezing • Clubbing ... • Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... mycobacteria Treatment
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... lumbar stenosis • Vascular ... axial T1 and T2 Treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... Arthritis, AS Treatment ... management #signs #symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... Intra-pulmonary vascular ... ) on room air Treatment ... resolution of symptoms