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diagnosis algorithm pathophysiology management pt abnormal anemia aptt arterial bleeding bruising dermatology intravascular petechiae purpura thrombosis venous adjusted age anesthesia
Simplified Coagulation Cascade and Differential Diagnosis #Coagulation #Cascade #Differential #Diagnosis #Intrinsic #Extrinsic #Pathway #Hematology
Simplified Coagulation ... Cascade and Differential ... Diagnosis #Coagulation ... #Cascade #Differential ... Extrinsic #Pathway #Hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... #PPT #PT #INR #Differential ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged ... Causes include : ... #differential # ... hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Bleeding #Bruising #Differential ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... Venous Thrombosis - Differential ... artery aneurysm: Causes ... intravascular coagulation ... APLS:PLT ↓ HEMATOLOGIC
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... vascular disorders, coagulation ... Platelet defects • Coagulation ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Thrombocytopenia • Prolonged ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Hemorrhage - Differential ... fatigue (e.g. prolonged ... intravascular coagulation ... (DIC) • Anti-coagulation
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... #CriticalCare #Hematology ... #Interpretation
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