1013 results
Cushing's Reflex - Pathophysiology
HYPERTENSION with a reflex BRADYCARDIA
 → ↑ ICP 
 → ↓ CBF
 →
Cushing's Reflex - Pathophysiology ... → ↑ Cerebral [CO2 ... Cushings #Reflex #Pathophysiology
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
#Pharmacology #Pathophysiology ... Drugs #Agents #COX
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

**
#Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways #COX
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
questions: - Co-ocupants ... - Alarm (for CO ... Confirm by measuring COHb ... the half-life of COHb
Chronic Hypercapnic Respiratory Failure Phenotypes
Pink Puffers (robust vent drive) ↑ their WOB when pulmonary mechanics gradually
drive) ↑ their WOB ... maintain the same WOB ... worsen (despite the CO2
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Pool → ↑ HMG-CoA ... sequestration #pathophysiology
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Pneumonia -> Cough, SOB ... signs #symptoms #pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICP Physiology: CO2 ... : • Low CO2 = ... CPP) • High CO2 ... Pressure #ICP #Pathophysiology
HFNC compared to NIV
HFNC:
- Comfort - Higher comfort  Eating, drinking and speaking less impaired 
-
Mostly reduced - CO2 ... Nasopharyngeal CO2 ... EELV, Reduced WOB