26 results
Causes of CSF Lymphocytic Pleocytosis - Differential Diagnosis
Viral: Arbo, Adeno, Herpes, Entero, HIV
Fungal: Cryptococcus, Cocci, Histo,
Causes of CSF Lymphocytic ... Cryptococcus, Cocci ... Leptomeningeal, Lymphoma, GPA ... Differential #Diagnosis #Causes
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- rule out non-ICU ... vs ICU causes ... gastroenterology #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... vasculitis - GPA ... Differential #Diagnosis #hematology ... #rheumatology #
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... intracellular, Aerobic - Cocci ... Peripheral smear - Cocci
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... ANCA (C-ANCA): GPA ... eGPA, MPA >>> GPA ... diagnosis #algorithm #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... (8%) - Gm - cocci ... Effusions: - Hematologic ... Osteochondroma Hematologic ... Knee #Effusions #causes
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
: Urine Common Uses ... , Post-partum, ICH ... rapid injection; Nausea ... #Pharmacology #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... #dermatology #rash ... #diagnosis #rheumatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... vasculitis (5%): PAN > GPA ... Vasculitis #dermpath #dermatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... unnecessary and cause ... Transfusion #Thresholds #Hematology