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Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... clinical context and signs ... inflammatory markers • Cardio-renal ... CK-MB, NT-proBNP, cardiac ... imaging #Acute
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... significant portal HTN Signs ... obstruction) • Lack of signs ... Post-Hepatic: • Cardiac ... • Cirrhosis/acute
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... , DIC, TMA • Cardiac ... Disease #diagnosis #management ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... WBC >100k, + lab signs ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... Myositis • Onset: Acute ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... orbital pain, (Sub)acute ... Unilateral • Signs ... Neuritis #Diagnosis #Management ... #treatment #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... ideally limit for acute ... Arthritis #diagnosis #management ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... - Autoimmune Rheumatologic ... #Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Rare: DAH, acute ... initiation • Differential ... , Anaphylaxis, Acute ... APML #diagnosis #management ... #hematology #oncology
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