13 results
Medications for Treatment of Acute Gout
 - NSAIDs
 - Colchicine (Colcrys)
 - Corticosteroids
#Acute #Gout #Medications #Treatment
Medications for Treatment ... of Acute Gout ... #Gout #Medications ... #Treatment #Management ... #AAFP #Rheumatology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... medications • Acute ... • Colchicine: Acute ... #diagnosis #management ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... , DIC, TMA • Cardiac ... Disease #diagnosis #management ... #treatment #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... cortical bone Treatment ... gout treatment; ... #diagnosis #management ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Gout - Management
Acute Gout Flare
 1) colchicine, NSAIDs, glucocorticoids
 2) Anakinra (IL-1 inhibitor)
When to Start Urate
Gout - Management ... Acute Gout Flare ... 3) 2+ gout flares ... #Management #treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... thrombosis, VTE) • Cardiac ... Behcet disease) Differential ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... very remarkable w/differential ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... nose, tracheal collapse ... purpura, joint & gut ... #Diagnosis #Rheumatology