21 results
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Management ... ascites removed • Acute ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Hepatorenal Syndrome ... Diagnosis and Management ... • Maintains cardiac ... #Hepatorenal #Syndrome ... #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... INR, bilirubin, albumin ... Post-Hepatic: • Cardiac ... • Cirrhosis/acute ... Diagnosis #causes #hepatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Pneumothorax, Cardiac ... Abdominal compartment syndrome ... Differential #Diagnosis #criticalcare ... #algorithm #treatment ... #management
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
essential to determine treatment ... CCB, BB, BRASH syndrome ... Pneumothorax, Cardiac ... pancreatitis, low albumin ... guyton #curves #criticalcare
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
hepatitis - Cardiac ... thrombosis (Budd-Chiari syndrome ... Veno-occlusive disease - Acute ... cirrhosis - Nephrotic syndrome ... Differential #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... Skeletal muscle, cardiac ... Skeletal muscle, Cardiac ... • Gilbert's syndrome ... #differential #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology