18 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty ... (AFLP) Three syndromes ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... #Pregnancy #hepatology ... #obstetrics #obgyn ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ascites removed • Acute ... • Hepatorenal syndrome ... #Indications #Management ... Cirrhosis #treatment #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... Skeletal muscle, cardiac ... Skeletal muscle, cardiac
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... Skeletal muscle, cardiac ... Skeletal muscle, Cardiac ... • Gilbert's syndrome ... #differential #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Post-Hepatic: • Cardiac ... • Budd Chiari syndrome ... • Cirrhosis/acute ... sarcoidosis) • Liver
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Rare: DAH, acute ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology