22 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... age and sex) • Cardiac ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome ... #management #oncology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... • Tumor lysis syndrome ... glycosides • High acute ... dietary intake • Blood ... inhibitor • Cardiac
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... Initial workup ... abnormalities • Cardiac ... MatthewHoMD #TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... leukapheresis - TLS ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... grade lymphoma & Acute ... #TLS #oncology ... #management #UricAcid
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... Investigations: full blood ... syndrome: troponin ... imaging #Acute
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... An acute rise or ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... #Hypertension #Workup
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Causes of acute ... Irritable bowel syndrome ... leukocytes and occult blood ... Chronic #Diarrhea #management ... #algorithm #workup
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... HIV, Influenza, TSS ... UA positive for blood ... Differential #Diagnosis #Management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... Acidosis, Cell Lysis (TLS ... reabsorption) Workup ... clear cause) Management ... line, stabilizes cardiac