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diagnosis hematology anemia treatment algorithm mds syndromes aplastic apml arrhythmias arterial autoimmune behcet cardiology carotidsinussyndrome cd4 cerebralhypoperfusion chf classification clinical
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... old, ~10,000 new cases ... #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... blood count with differential ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #hematology #secondary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Hypothyroidism, Myelodysplastic ... syndrome - Dr ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
be divided into cardiac ... frequently benign causes ... carotid sinus syndrome ... syncope (ruling out differential ... further guide management
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... valves - Infected cardiac ... coagulation and other causes ... #differential #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
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