11 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Characteristics of Old and ... #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... aspiration #Potassium #Binding ... medications #pharmacology ... #table #comparison ... #binders
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
require phosphate binding ... since they are not able ... restricted due to hypercalcemia ... Only* #CKD #Nephrology ... #Dose #Dosing #Pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... intracellular calcium causes ... - Hyperkalemia ( ... binds to the same
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... of Hyporeflexia and ... Hyporeflexia: • Hypercalcemia ... differential #diagnosis #table ... #neurology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology # ... Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... Treatment #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... fluid/Lactated ringers ... per day until stable ... Diagnosis #Management #causes ... #treatment #nephrology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
vera, Licorice - Causes ... hypokalemia, increasing ... risk of digoxin ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia • Hypercalcemia ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table