15 results
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #management #algorithm ... #pharmacology # ... #medications #table
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
• Hypovolemic: Bleeding ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... management #comparison #table
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
alpha-blockers, leading ... palmetto - Increases bleeding ... palmetto - Increases bleeding ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Algorithm for Diagnosis of Acute Gastrointestinal Bleeding
 • Endoscopy
 • Colonoscopy
 • CT Angiogram
 • Catheter
Algorithm for Diagnosis ... Gastrointestinal Bleeding ... Endoscopy • Colonoscopy ... LouLectures #Algorithm ... Gastrointestinal #Bleeding
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
per treatment table ... and procedural bleeding ... with a very low bleeding ... Management #Treatment #pharmacology
Additional Modalities for Workup of GI Bleed (Other than EGD + Colonoscopy)

Pill endoscopy
 • Able to
Other than EGD + Colonoscopy ... endoscopy • Able ... bleed may obscure bleeding ... Enterography • Able ... gastroenterology #table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
DOACs thereby leading ... metabolization leading ... #Interactions #Table ... #Pharmacology
Lower GI Bleed - Management Algorithm

Suspected lower GI bleeding (LGIB):
 • Hematochezia 
 • Melena +
Bleed - Management Algorithm ... Suspected lower GI bleeding ... upper GI bleed) vs Stable ... GIBleed #management #Algorithm
Algorithm for the management of patients presenting with acute Lower GI Bleed
High-risk patients
Multiple high-risk clinical features.a
Algorithm for the ... symptorns of ongoing bleeding ... for unprepped colonoscopy ... hernodynamically stable ... , no ongoing bleeding
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
roentgenography • Bleeding ... with specific bleeding ... Diuresis #Nephrology #Pharmacology ... #Medications #Table