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diagnosis differential algorithm oncology management myelodysplastic pancytopenia treatment causes chronic cll criticalcare disorders lactate lactic leukemia lymphocytic macrocytic mcv myelodysplasia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... Deficiency • MDS ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin color ... Hypocellular/Hypoplastic MDS ... #hematology #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Can progress to MDS ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Non-hemolytic: ACD, Aplastic ... anemia, CKD • ... Reticulocytosis, MDS ... Matthew Ho, MD ... Differential #Diagnosis #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Diagnosis #Algorithm #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome (MD ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Matthew Ho, MD ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... sugars in the colon ... infographic by Nick Mark MD
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