5800 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... of alternative complement ... MPGN without complement ... MPGN #nephrology #diagnosis
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram
Humoral Immunity:
 •
Humoral Immunity and Complement ... T and B cells Complement ... PrathitKulkarni #complement ... #differential #diagnosis
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
- Differential Diagnosis ... Antibody/DAT+ - Complement ... #Differential #Diagnosis
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... ThePeanutKidney #Complement ... #differential #diagnosis
Lupus - Role of complement and anti-dsDNA for the detection of flares
Complement - ↓ Decreased
Anti-dsDNA -
Lupus - Role of complement ... detection of flares Complement ... biomarkers #antidsdna #complement ... #diagnosis #rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Mechanism: IgG and Complement-mediated ... Mechanism: IgM and Complement-mediated ... Anemia #hematology #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... #differential #diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
- Differential Diagnosis ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... #Differential #Diagnosis
Complement Deficiency Testing Algorithm
 • Normal CH50 and AH50 AND High suspicion for complement deficiency
 •
Complement Deficiency ... suspicion for complement ... ARUPConsult @ARUPLabs #Complement ... Algorithm #hematology #diagnosis
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... HUS (aHUS) - Complement-mediated ... #differential #diagnosis