116 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Effect of Selected Diseases ... on Complement Levels ... - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... constitutional symptoms • Treatment ... 80% - Low complement ... life-threatening • Treatment ... Evolution: Chronic disease
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Vasculitis - Anti-GBM Disease ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement ... , mitral valve disease
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
manifestations • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Treatment: • ... Erythematosus #SLE
Algorithm for the Treatment of Parkinson Disease With Predominant Postural Instability and Gait Impairment

#Management #Neurology #Parkinsons
Algorithm for the ... Treatment of Parkinson ... Disease With Predominant ... Neurology #Parkinsons #Disease ... #Medication #Treatment
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... treat non-renal SLE ... for worsening disease ... treat extra-renal SLE
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm
 • GI disorders: Celiac disease, Crohn's disease,
Differential Diagnosis Algorithm ... disorders: Celiac disease ... , Crohn's disease ... spondylitis, RA, SLE ... Differential #Diagnosis #Algorithm
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Tubulointerstitial diseases ... - Sickle cell disease ... transplant - SLE ... Tubulointerstitial diseases ... #Hyperkalemia #Algorithm