26 results
OPIOID SWITCHING AND TAPERING.

Long term opioid use results in physical (and potentially psychological) dependence. Opioids should
OPIOID SWITCHING ... Long term opioid ... sweating, anxiety, nausea ... #pharmacology #conversion ... #management #Guide
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Amyl nitrite - causes ... thiosulfate enhances conversion ... Cyanide #Toxicity #Toxicology ... Pathophysiology #Management
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... /IO/SQ for non-opioid ... search for other causes ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Diagnosis and Management ... no respiratory cause ... acute or chronic ingestion ... , Diaphoresis, Pulmonary ... Aspirin #Toxicity #Toxicology
Naloxone for Clonidine Overdose
Indication: Altered mental status, CNS depression or respiratory depression due to clonidine overdose
Dosing:
increase endogenous opioid ... Endogenous opioids ... move on to other cares ... Clonidine #Overdose #toxicology ... #management
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Noncardiogenic Pulmonary ... Noncardiogenic pulmonary ... Causes include: ... vascular congestion ... syndrome (ARDS) • Opioid
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet

An acute diffuse, inflammatory lung injury, leading to
leading to increased pulmonary ... permeability, lung congestion ... consistent with pulmonary ... there is no clear cause ... the underlying cause
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
(~6 hours post-ingestion ... Abdominal pain, nausea ... -24 hours post-ingestion ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Toxic Alcohol Ingestion: Isopropyl Alcohol
General concepts for toxic alcohols:
• Parent compounds (not metabolites) cause high osmolal
Toxic Alcohol Ingestion ... not metabolites) cause ... to lactate --> causes ... #Diagnosis #Management ... #Toxicology #Isopropyl
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... infections are caused ... presentations: • Pulmonary ... considered in certain cases ... IA #Diagnosis #Management