32 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear, HIV ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... When do you do a BM
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Coxsackie, CMV, EBV ... , HIV, HTLVI, Hantavirus ... diagnosis #management #treatment ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... workup, including BM ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Glucocorticoids, IL-1B, ATRA
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... EBV, CMV), Alcohol-related ... liver disease, ... #hepatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... when the CD4-cell count ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Encephalopathy Triad ... : The clinical ... and with low CD4 counts ... disorder #dementia #AIDS ... #Neurology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Investigations: full blood count ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... , HIV serology,
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... - HIV • Immune ... aplastic anemia Treatment ... from low blood counts ... Anemia #oncology #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... worsening of that disease ... be present: • AIDS ... noncompliance • Clinical ... initiation Clinical
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Campylobacter jejuni - HIV ... , CMV, EBV - Influenza ... Guillain-Barre Clinical ... #neurology