19 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... workup, including BM ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Glucocorticoids, IL-1B, ATRA
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Investigations: full blood count ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... #causes
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Coxsackie, CMV, EBV ... hemopathies, solid cancers ... diagnosis #management #treatment ... #rheumatology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... Absolute neutrophil count ... paradoxus • Beck triad ... differential #diagnosis #cancer
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Autoimmune disease, Cancer ... white blood cell count ... the underlying cause ... • Treatment of
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... when the CD4-cell count ... should be based on clinical ... Antimicrobial treatment ... recovery (CD4-cell count
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... B-LNH), solid cancers ... Treatment: • ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... : • Platelet count ... Treat primary cause ... #treatment #management ... #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... - HIV, CMV, EBV ... Guillain-Barre Clinical ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... from low blood counts ... Anemia #oncology #hematology