17 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... - HIV, CMV, EBV ... meningococcal, H1N1) Clinical ... Clinical Features ... #neurology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... - Differential ... workup, including BM ... Rebound effect from treatment ... Glucocorticoids, IL-1B, ATRA
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... white blood cell count ... and cauda equina TREATMENT ... specific therapy, the clinician ... diagnosis #management #neurology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Investigations: full blood count ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... #AKI #Workup #Algorithm
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... when the CD4-cell count ... should be based on clinical ... Antimicrobial treatment ... #differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Idiopathic • Infections ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... from low blood counts
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
toon • Spinal infection ... cord • Guillain-Barre ... MRI- Sagittal, axial ... T1 and T2 Treatment ... diagnosis #causes #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... albicans • Epstein Barr ... Leishmaniasis Differential ... therapy (COAT TRIAL
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Reversible course Differential ... Diagnosis: • Infection ... white blood cell count ... epilepticus Treatment