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diagnosis rheumatology differential clinical photo algorithm antimda5 antimda5dm antinxp2 antinxp2dm arterial autoimmune drugrelated embolism erythematosus exanthema flexural gangrenosum intertriginous lupus
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Sarcoidosis • Crohn's ... gangrenosum • IBD ... Sarcoidosis #dermatology ... #joint #pain #skin
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... the disease and ILD ... increases and ILD ... prevalence of RP-ILD ... dermatology #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... - Protein C deficiency ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... and pain of the joints ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... Syndrome #diagnosis #dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... Muscle atrophy may cause ... : • ILD was diagnosed ... • In severely ill ... #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Malignancy (e.g. hematologic ... disease • Prolidase deficiency ... Arthritis: • Joint ... arthropathy • 90% joints
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Gangrenosum (PG) 50 M Crohn ... conditions such as IBD ... -1β, IL-8, IL-17 ... medications in most cases ... clinical #photo #dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... Syndrome: Fever, joint ... • ANA < 20 % IBM ... statins - probably caused ... Myositis #Myopathy #rheumatology
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
+burning rash groins ... warm,red patch groins ... MCQ highlights a case ... Washington University ID ... clinical #photo #dermatology
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