37 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... : • Pauci-Immune ... Cryoglobulinemia) • Immune ... Investigations • Labs: CBC ... #differential #
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... Immune-mediated ... diagnosis and treatment ... • Sjögren syndrome ... #inflammatory #differential
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Inflammatory Syndrome ... (IRIS) - Pathophysiology ... factors: - Low CD4 ... duration or OI treatment ... #Inflammatory #Syndrome
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... Guillain-Barré syndrome ... antisynthetase syndrome ... , immune-mediated ... Statin Treatment
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Capillary leak syndrome ... • Tumor lysis syndrome ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... Non-inflammatory Causes Immune-mediated ... diagnosis and treatment ... recessive—Usher syndrome ... noninflammatory #differential
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... 3) UOP > 0.5 cc ... criticalcare #algorithm #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... Unknown cause Treatment
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders #Classification ... #pathophysiology