185 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Complement Levels - C3 ... , C4 • SLE C3 ... • MCGN type 1 C3 ... ↓ C4 ↓↓ • Cryo ... C3 ↓ C4 ↓↓ •
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Mediated: • ↓C3 ... Membranoproliferative • ↓C4: Lupus ... Cryoglobulinemia • Normal C3
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... Class II or V lupus ... proteins domain: Low C3 ... or low C4, Low C3
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... SUBACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... Low complement (C3
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Cryoglobulinemia (85%), C3 ... S - Systemic Lupus
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
IgG positive, C3 ... IgG negative, C3
Treatment Options for Lupus Nephritis

#Lupus #Nephritis #Treatment #management #nephrology
Treatment Options for Lupus ... Nephritis #Lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Acute cutaneous lupus ... Subacute cutaneous lupus ... Complement levels (C3 ... disease activity • C3
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Manifestations of Systemic Lupus ... ) #Systemic #Lupus
Herpes Zoster C3 Distribution: Dermatomally distributed vesicles, many of which have coalesced, 
in patient with HZV
Herpes Zoster C3 ... HZV #Dermatomal #C3