17 results
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis - Induction, Consolidation and Maintenance Therapy

Table 2. Antifungal Treatment Recommendations
Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... management #meningitis #cryptococcus
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... Aspergillus fumigatus, Cryptococcus ... .2015.10.012 #Antifungal
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
- Species and Antifungal ... Therapy Cryptococcus ... Invasive #Yeasts #Antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... : Zygomycetes, Cryptococcal ... Overview #Polyenes #Antifungal
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
negative culture Brain ... : Aspergillus, Cryptococcus ... nocardia - Fungal: Cryptococcus ... Coccidiomycosis, Cryptococcus
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... lack activity vs Cryptococcus ... Echinocandins #Antifungal
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
infections: Severe cryptococcal ... #Flutycosine #Antifungal
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
histoplasmosis, cryptococcus ... RingEnhancing #Lesions #Brain
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
- Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... of mold-active antifungals
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
pulmonary infections) Cryptococcus ... galactomannan, cryptococcal ... initiation of targeted antifungal ... identification and antifungal