12 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... Alkaline phosphatase ... Chemistry #Tests #Laboratory ... #Pathophysiology ... #Diagnosis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Interpretation Alanine ... , lungs, RBCs Alkaline ... #Tests #LFTs #Laboratory ... Interpretation #diagnosis ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... elevation and clinical context ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology ... #diagnosis
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... deficiency - Anemia ... leads to chronic anemia ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... PBC Labs: • Alkaline ... or higher • Liver ... #workup #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... appropriate clinical context ... - assess other laboratory ... Arterial Oxygen Content ... 30mmHg) - Severe anemia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... venipuncture sites Laboratory ... DIC • Severe Liver ... #Coagulation #diagnosis ... treatment #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
the presence of anemia ... more time for the laboratory ... profile, including liver ... (to support a diagnosis ... #workup #diagnosis