70 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... signs #symptoms #diagnosis
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
- Differential Diagnosis ... Chronic liver disease ... Chlamydia (*Fitz-Hugh-Curtis ... #Differential #Diagnosis ... #hepatology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in macrophages Diagnosis ... ß-glucocerebrosidase activity ... #Diagnosis #Signs
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
normal factor activity ... 50% of normal activity ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... Individual factor activity ... those with severe disease ... Management #treatment #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... vessels with a certain ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Droplets that contain ... Chronic kidney disease ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Leakage’ symptoms of active ... Hashimoto’s disease ... of Hashimoto’s disease ... Endocrinology #Diagnosis ... #Pathophysiology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
with more severe disease ... Used to monitor disease ... activity Anti-Ro ... #SLE #Summary #diagnosis ... #rheumatology #
Erythema Annulare Centrifugum (EAC),
This is erythema annulare centrifugum (EAC), one of the “figurate erythemas.” These lesions
lags behind the active ... drugs, systemic disease ... clinical #photo #dermatology ... #skinrash