12 results
diagnosis rheumatology management differential erythematosus signs systemic classification dermatology syndrome autoantibodies behcet clinical complications dil disease drug drugs manifestations medications
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Rare (SSA+ for cutaneous ... • Treatment: ... Lupusreference #druginduced ... #lupus #sle #comparison
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... , Cutaneous mimickers ... Lupusreference #SLE ... autoantibodies #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... lupus: scaly annular ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Symptoms Distinguishing Groups of Cutaneous Drug Reactions IgE-mediated reactions: • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Groups of Cutaneous ... to hours into treatment ... Onset days into treatment ... dermatology #clinical #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute cutaneous ... scarring • Subacute cutaneous ... inflammation Cutaneous ... : • Symptoms limited
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... is rare in DIL, SCLE-DIL ... Rare (SSA+ for cutaneous ... • Treatment: ... Lupusreference #DrugInduced
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... GBS), systemic lupus ... erythematosus (SLE ... after DC Statin Treatment ... diagnosis #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
vasculitis) • Cutaneous ... meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... with drug-induced SLE ... for 1 year of treatment ... Lupusreference #DrugInduced ... #SLE #Systemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
aphthous ulcers, cutaneous ... such as systemic lupus ... Presentation - Systemic Symptoms ... strong sign of cutaneous ... vasculitis, and SLE
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