15 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Rare (SSA+ for cutaneous ... constitutional symptoms ... • Treatment: ... #sle #comparison
Immunosuppressive Medications in Systemic Lupus Erythematosus (SLE)
 - MTX (oral, subcutaneous)
 - AZA (oral) 
 -
Immunosuppressive Medications ... in Systemic Lupus ... Erythematosus (SLE ... #Systemic #Lupus ... Erythematosus #treatment
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... , Cutaneous mimickers ... Lupusreference #SLE ... autoantibodies #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... scarring • Subacute cutaneous ... inflammation Cutaneous ... : • Symptoms limited ... activation and/or medications
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... lupus: scaly annular ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Groups of Cutaneous ... to hours into treatment ... Onset days into treatment ... dermatology #clinical #comparison
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... GBS), systemic lupus ... erythematosus (SLE ... after DC Statin Treatment ... diagnosis #management #treatment
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... is rare in DIL, SCLE-DIL ... Rare (SSA+ for cutaneous ... constitutional symptoms ... • Treatment:
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment
Algorithm for the Diagnosis of Serotonin Syndrome
 - Serotonin syndrome is thought to be caused by
administration of medication ... initiation of treatment ... (see below) and ... Syndrome #Algorithm #Symptoms