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differential hemolytic dyspnea extravascular intravascular sob abnormal abnormalities agglutinin bronchiectasis chronic classification cold cryofibrinogenemia disease hyperpnea normocytic patterns phtn physicalexam
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Warm AIHA • Cold ... Complement-Mediated • Cold ... anemia • ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... Algorithm Decreased ... #Algorithm #Causes ... #Hematology
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm Pulmonary Arterial Hypertension • Idiopathic • Associated with:
Causes of Pulmonary ... Algorithm Pulmonary ... Hypoxemia: • COPD ... Sleep-Disordered Breathing ... #Algorithm #Causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Diagnosis: • hemolytic ... anemia • Cold ... sensitize red blood cells ... #anemia #hematology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Causes of Chronic ... • Asthma • COPD ... Pneumonia • ARDS • COPD ... - Other • Anemia ... #Algorithm #Causes
Tachypnea - Differential Diagnosis Framework Definitions • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults •
- Differential Diagnosis ... Pulmonary Causes ... • Asthma • COPD ... effusion/Tamponade Hematologic ... : • Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... cells - Consider ... Agglutination - Cold ... #Diagnosis #Algorithm ... #workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • AIHA: warm, cold ... #Diagnosis #causes ... classification #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... - Asthma - COPD ... Transverse myelitis • Hematology ... : - Anemia • ... #causes #pulmonary
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