1782 results
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... Endotoxins, Toxins, Cytokines ... production • Treatment ... BrighamChiefs #Fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
pro-inflammatory cytokines ... hemophagocytosis and cytokine ... disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
activation and cytokine ... following: • Fever ... • Bicytopenia Treatment ... diagnosis #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology: • Cytokine ... Subacute-Acute: • Common: fever ... Renal Failure Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
pro-inflammatory cytokines ... • Clinical: fever ... Unknown cause Treatment ... diagnosis #management #treatment
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
night sweats, fever ... disease Imaging and Treatment ... ), Recombinant cytokines
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... GCA is almost never ... /Symptoms: - Fever
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... Mountain spotted fever ... , Drug fever
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
Leptospirosis, Rat-bite fever ... infectiousdisease #fever ... #management #treatment