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diagnosis differential clinical algorithm management neurology video physicalexam cardiology radiology pocus pathophysiology nephrology pulmonary dermatology pharmacology photo treatment table syndrome
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
keratinocytes release cytokines ... hair follicles -> causes ... Livedo Reticularis, Vasculitis
Causes of Fever: IMADE Mnemonic INFECTION • Infection 1.0 - Common & Localizing: Base Rate • Infection
Causes of Fever: ... Schnitzler • GPA • Vasculitides ... increased inflammtory cytockines ... IMADE #Mnemonic #Causes
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Hypocomplementemic Urticarial Vasculitis ... Anaphylatoxins, Chemokines, Cytokines ... Formation -> Vasculitis ... Hypocomplementemic #Urticarial #Vasculitis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... palpation - Vasculitic ... Signs #Symptoms #Vasculitis
Hypothermia in Sepsis - Pathophysiology • 20% of septic pts → HYPOTHERMIA • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... Cryoglobulinemic vasculitis ... syndrome • IgA vasculitis ... Small #Vessel #Vasculitides ... #vasculitis #differential
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... eosinophilopoietic cytokines ... Common causes: ... disease Rare causes ... Differential #Diagnosis #Causes
Vasculitis: In this instance, the vasculitic skin lesions were secondary to Haemophilus endocarditis. Photo credit, Josh Fierer,
Vasculitis: In this ... instance, the vasculitic ... Dermatology #SkinRash #Vasculitis
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... medium vessel vasculitis ... and small vessel vasculitis ... Large vessel vasculitis
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