1138 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Prednisone 5mg/kg/day ... severe • Rare: DAH ... (sepsis), PE, DAH
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Inappropriate ADH ... Insipidus - Inadequate ADH ... SIADH - Excess ADH ... Comparison #Table #Pathophysiology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Anemia (AIHA) Pathophysiology ... IgG mediated - DAT ... IgM mediated - DAT ... Hemolytic #Anemia #Pathophysiology
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Hyponatremia - Pathophysiology ... permeability increased - ADH ... independent / ADH ... #Hyponatremia #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... antagonists 6) ADH ... Adenosine #Nephron #Pathophysiology
Pathophysiology of The Nephron - Electrolyte and Water Exchange

The nephron — electrolyte and water exchange. 
180
Pathophysiology ... of sodium per day ... of sodium per day ... #Pathophysiology
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
#CAH #algorithm ... Endocrinology #Adrenal #pathophysiology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Hypovolaemia → ADH ... SaltWasting #SIADH #Pathophysiology
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
enzymes affecting CAH ... Pathway #metabolism #pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology