15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... initiation • Differential ... #APML #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL can present as ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: CANOMAD, DADS-M ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
consistent with a diagnosis ... The video highlights ... #clinical #video ... #ophthalmology ... #physicalexam #neurology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Grafts, Valves, AS ... Drug-associated, PCH, Evans Syndrome ... Laboratory Tests ... #Diagnosis #hematology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
the follow up video ... the hospital, diagnosed ... #PhysicalExam # ... clinical #video ... #ophthalmology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Positive pathergy test ... is a skin prick test ... Behcet disease) Differential ... Reactive Arthritis, AS ... inhibitors • Uveitis- Ophthalmology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... Diagnosis Framework ... such as the whispered ... II ○ Susac’s syndrome ... #Diagnosis #otology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology