36 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... #nephrology #causes
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... and Evidence Summary ... unnecessary and cause ... ALI is the deadliest ... /vmoitra) #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... #management #treatment ... #summary #rheumatology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Clinical Exam: ... chills, malaise Ddx ... Treatment: admission ... patient admitted for treatment ... MH/CCF/CWRU EM
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... help and inform clinical ... • Diagnostic ... thoracotomy is a better treatment ... #Tamponade #Anesthesiology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... EGPA) • Renal: (AKI ... antibody, Anti-GBM ... Goodpasture's cause ... #management #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... and Management Summary ... Causes of Rhabdomyolysis ... Dermatomyositis Clinical ... + myoglobin AKI
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... Coxsackie, CMV, EBV ... , DIC, TMA • Cardiac ... #management #treatment
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... require prolonged treatment ... an appropriate critical ... #Anaphylaxis #Anesthesiology ... Intraoperative #Checklist #Diagnosis