22 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... unnecessary and cause ... ALI is the deadliest ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... lethargy, hematuria, cardiac ... with tetany or cardiac ... diagnosis #management #hematology
This is a quick overview of hormonal acne treatment for the medical student and resident.

Keep in
hormonal acne treatment ... #treatment #photo ... Trivedi M, Clark AK ... Koo EB, Petersen ... data review of 70 cases
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Coxsackie, CMV, EBV ... , DIC, TMA • Cardiac ... diagnosis #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... severe clinical ... thiamine) Late: • Cardiac ... • Delirium DDX ... hyperparathyroidism Treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... helmet cells DDX ... + Bleeding Treatment ... #treatment #management ... #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... nose deformity • Cardiac ... (UPC) ratio • Cardiac ... Goodpasture's cause ... diagnosis #management #treatment
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
recommendations, treatments ... #diagnosis #causes ... Petersen EBM, Skov ... EL, Richardson IM ... (5):1821-1829. doi