49 results
SALT-ED Trial - Balanced Crystalloids versus Saline in Noncritically Ill Adults

N Engl J Med 2018; 378:819-828
//www.nejm.org/doi ... hospital-free days between treatment ... crystalloids and treatment ... #AKI #MAKE30 #VisualAbstract ... #EBM
Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline
hospital-free days between treatment ... - Stage 2 AKI ... //www.nejm.org/doi ... #AKI #VisualAbstract ... #LR #EBM #Nephrology
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
• Na intake/saline ... Resolution of AKI ... Polydipsia • Central DI ... Differential #Diagnosis #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... ANCA, ANA, Anti-GBM ... inflammatory markers • Cardio-renal ... CK-MB, NT-proBNP, cardiac ... Diagnosis #nephrology #causes
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
(LR) vs Normal Saline ... Causes AKI: - ... May Cause Hemodynamic ... Acidosis worsens cardiac ... contractility • Saline
Cardiac etiologies of syncope (red line above) have the highest associated mortality! #EBM #EM #IM #Cardiology
Cardiac etiologies ... of syncope (red line ... #EBM #EM #IM #Cardiology ... Syncope #Survivial #Cardiac
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
symptoms (HA, nausea ... Medical history (cardiac ... history #Diagnosis #EM ... #IM #Nephro #Hyponatremia
Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest

N Engl J Med 2017; 376:1737-1747 https://www.nejm.org/doi/full/10.1056/NEJMoa1601891

Conclusion: Bystander
Out-of-Hospital Cardiac ... //www.nejm.org/doi ... death from any cause ... VisualAbstract #BLS #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 2018 - Cardiac ... unnecessary and cause ... surgical, GIB, and cardiac ... ALI is the deadliest ... /vmoitra) #EBM