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clinical diagnosis sign physicalexam symptoms video pocus cardiology radiology neurology pathophysiology management pulmonary differential ultrasound msk pediatrics endocrinology orthopedics algorithm
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
Radiculopathy: Signs ... /Neck Pain • Decr ... paralysis) • Decr ... • Spurling's sign ... pain Lasegue's sign
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Proteolytic enzymes • Decr ... ICAM-I, VCAM-I) • Decr ... > Keratoconus Signs ... Ring • Munson's sign ... • Rizutti's Sign
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Post-menopausal women -> Decr ... smoking, etoh, decr ... pathophysiology #signs
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Decreasing ACTH -> Decr ... and action -> Decr ... osteocytes -> Decr ... pathophysiology #signs
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Manifestations Decr ... Goblet cell loss & Decr ... peripheral dots • Decr ... ophthalmology #diagnosis #signs
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Headache • Decr ... confrontation • Decr ... Valvular damage • decr ... Overproduction #diagnosis #signs
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Metabolism -> Decr ... into cells -> Decr ... of proteins -> decr ... Serum PO4 -> decr ... pathophysiology #symptoms #signs
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
/agitation - Decr ... hopelessness - Decr ... pleasure - Decr ... Pathophysiology #Signs
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... conjunctivitis - Decr ... endocrinology #symptoms #signs
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Diagnosis • Decr ... Disease #Diagnosis #Signs
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