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Water Deprivation Test - Differential Diagnosis of Diabetes Insipidus (DI) Concept of WDT: endogenous vasopressin secretion is
Diabetes Insipidus (DI ... Diabetes #Insipidus #DI
Hypernatremia Classification and Features According to Volume Status - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - DI ... Central Dl, Partial DI ... , Gestational DI ... , Nephrogenic DI
Polyuria - Differential Diagnosis Solute Diuresis • Na intake/saline • Glucosuria: Hyperglycemia, SGLT-2 inhibitors • Urea: Exogenous
Polydipsia • Central DI
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
nephrology #insipidus #DI
Hypernatremia - Diagnostic Evaluation Algorithm Step 1: Consider history. Most patients presenting with hypernatremia are either very
If patient has DI
Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge Give desmopressin (intranasal, SQ, IV) and monitor UOsm every
Diabetes #Insipidus #DI
Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
• Nephrogenic DI
Types of Renal Calculi Calcium oxalate - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
of cysteine and di-basic
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
urine osm (in DI
Two-step Copeptin algorithm for differential diagnosis of Diabetes Insipidus (DI) Baseline Copeptin < 21.4 pmol/L: • Arginine-stimulated
Diabetes Insipidus (DI ... partial Central DI ... → Nephrogenic DI ... Diabetes #Insipidus #DI
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