287 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
- Differential Diagnosis ... and non-hematologic ... Myelodysplasia Nutritional deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... blood loss (Fe deficiency ... Non-infectious (malignancy, rheumatologic ... #Differential #Diagnosis ... causes #Platelets #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... • Folate Deficiency ... • TTP/HUS • DIC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... elevated in: • DIC ... Thromboplastin #laboratory #hematology ... #diagnosis
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
B12 and Folate Deficiency ... • B12 Deficiency ... #MMA #folate #deficiency ... #VitaminB12 #diagnosis ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Acute hemolysis, deficiency ... #Differential #Diagnosis ... #Algorithm #hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
• 812, Folate Deficiency ... #differential #diagnosis ... #algorithm #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Underproduction Diagnostic ... Algorithm - Iron deficiency ... and/or folate deficiency ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Non malignant hematologic ... malignancy • Iron deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology