30 results
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
leukemia (APL) ... In addition to APL ... myeloid leukemia (AML ... ) t(8;21), AML with ... Rods #AuerRods #APL
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
leukemia (blood ... overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL (Acute Lymphoblastic ... -> AML: Blast crises ... Lymphadenopathy AML ... cutaneous plaques) AML
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... are typical for acute ... myelogenous leukemia (AML ... #Blood #Smear # ... Rods #AuerRods #AML
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Diagnosis Algorithm ... Acute • Myloid ... (AML) - CD13, CD33 ... • Lymphoid (ALL
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Diagnosis Algorithm ... Lymphoblastic Leukemia (ALL ... ) • Acute ... Myeloid Leukemia (AML ... endocrinology #causes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... initiation • Differential ... Differentiation #Syndrome #APML ... #diagnosis #management
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome - Causes ... hyperleukocytosis (AML ... #Differential # ... Diagnosis #Treatment ... #Management
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... the total white blood ... histamine in their granules ... #Diagnosis #causes
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... perfusion, recheck blood ... #Hypotension #Differential ... Intraoperative #Checklist #Diagnosis ... #Management #Workup