29 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... overt cytoplasmic granules ... #Auer #Rods #Acute ... promyelocytic #leukemia #APL ... #Hematology #Clinical
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
NON-WEIGHT BEARING CHILD ... RED FLAGS - In all ... Algorithm #Pathway #Child ... #Peds #Pediatrics ... #Diagnosis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... She was diagnosed ... with acute promyelocytic ... decreased secondary granules ... also described in acute
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... distinctive primary granules ... #Leukemia #Hematology ... #Oncology #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... to delivery of child ... to delivery of child ... AFLP #obstetrics #hematology ... #diagnosis #table
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
years old) - Acute ... School-aged - Acute ... Adolescence - Acute ... Malignant #Childhood #Peds ... #Pediatrics #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... unless severe APLS ... #hematology #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... histamine in their granules ... translocation • Acute ... thrombocythemia • Acute ... #causes #hematology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
AIP: acute interstitial ... #LungDisease #CTILD ... #Diagnosis #Differential ... Table #Pulmonary #Rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Algorithm Acute ... • Myloid (AML ... Blood #Disorders #hematology ... #Differential #Diagnosis