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differential oncology algorithm management monoclonal alkaline alp dermatology gammopathy mgus pediatrics phosphatase significance aflp apml atopic atopy biliary bismuth bleeding
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
NON-WEIGHT BEARING CHILD ... RED FLAGS - In all ... neurology, back pain Haematology ... #Peds #Pediatrics ... #Diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... • Scleroderma renal ... • Catastrophic APLS ... #differential #diagnosis ... #hematology #hemolysis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... , CML, AML, APML ... distinctive primary granules ... #Leukemia #Hematology ... #Oncology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Pregnancy - Renal ... #Differential #Diagnosis ... #Algorithm #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... opacities • Diagnosis ... Anaphylaxis, Acute Renal ... unless severe APLS ... #hematology #oncology
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... TMAs but (almost) all ... /o significant renal ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... fractures • Dental ... Difficulty walking Diagnosis ... Hyophosphatasia #hepatology ... #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - PNH - APLS ... Decreased Support Of Dermal ... #Differential #Diagnosis ... #hematology #rheumatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
cataracts, and renal ... of platelet α-granules ... #differential #diagnosis ... #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Features: POEMS, AL ... Cryoglobulinemia Renal-centered ... #Differential #Diagnosis ... #hematology #oncology
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