444 results
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
synthesis and food (dairy ... VitaminD #Metabolism #endocrinology
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework

Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
CVD: 1.6 μg/kg daily ... CVD: 12.5-25 μg daily ... Diagnosis #algorithm #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
• 500mg once daily ... → 500mg 2x/daily ... DM2 #diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
(Lixisenatide) Daily ... (Liraglutide) Daily ... injected once daily ... Diabetes #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Saxenda, Victoza) - Daily ... (Ozempic), or daily ... DM2 #diabetes #endocrinology
Bisphosphonates for Osteoporosis Treatment or Prevention 

Bisphosphonates are common medications used in the treatment and prevention
frequencies, from daily ... #Pharmacology #Endocrinology
PCOS Treatment
1st line = weight loss
 • 5-10% weight loss can restore ovulatory cycles
 • Improvement
chronic anovulation Daily ... Treatment #management #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
Dosing: 3 mg daily ... maintenance dose of 7 mg daily ... increase to 14 mg daily ... non-inferior to daily ... #Pharmacology #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Calculate total daily ... comparison #table #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Estimating the Total Daily ... #pharmacology #endocrinology