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diuretics nephrology table medications action algorithm causes classes comparison diagnosis differential diuresis drugs effects electrolytes ethacrynic excretion hypercalcemia hypokalemia indications
Diuretics - summary table Thiazides and Related Diuretics: HCTZ, Chlorthalidone, Metolazone, Indapamide, Bendroflumethiazide Loop Diuretics: Furosemide, Ethacrynic
summary table Thiazides ... Furosemide, Ethacrynic acid ... #pharmacology # ... table #thiazide ... #aldosterone
Diuretic Electrolyte Excretion Effects Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid - Thiazide Type
-, HCO3-, Uric Acid ... - Thiazide Type ... - Loop - Aldosterone ... electrolytes #effects #pharmacology
Ethacrynic acid - Conversion Only loop diuretic without a sulfonamide substituent. Rarely used alternative in patients who have
Ethacrynic acid ... - Conversion Only ... loop diuretic without ... mg = Ethacrynic acid ... #Conversion #pharmacology
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
urearetics) 3) Loop ... furosemide) 4) Thiazides ... 5) Aldosterone ... Action #nephrology #pharmacology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Losses: • Normal Acid-Base ... Ureterosigmoidoscopy • HTN, Low Aldosterone ... • HTN, High Aldosterone ... • HTN Absent: Loop ... and thiazide diuretics
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop ... #nephrology #conversion ... #loop #thiazide
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
+2Cl- Symport (Loop ... Bumetanide, Ethacrynic acid ... +CI- Symport - Thiazide ... Receptor Antagonists (Aldosterone ... Diuresis #Nephrology #Pharmacology
Pharmacologic Options for Hypercalcemia Associated with Cancer Rehydration with NS followed by loop diuretics • IV normal
Pharmacologic Options ... NS followed by loop ... Pamidronate, Zoledronic acid ... Inhibits vitamin D conversion ... drugs #treatment #pharmacology
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