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diagnosis joint pain erythematosus lupus management msk signs sle symptoms systemic dermatology disease vasculitis adultonset antimda5 antimda5dm approach autoantibodies autoimmune
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... #joint #pain #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... migrans • Lyme disease ... • Rheumatic fever ... #skin #rashes #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad: Fever ... , Arthralgia/arthritis ... fraction < 20% Differential ... management #treatment #rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Juvenile idiopathic arthritis ... • Rheumatoid arthritis ... falls (like a wave ... Brucellosis Faget's Sign
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... • Rheumatic fever ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) Differential Diagnosis ... SLE, Reactive arthritis ... SLE, Reactive Arthritis ... diagnosis #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... , Fever, Serositis ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Coronary arteries - Fever ... Vasculitis: • Fevers ... purpura: strong sign ... #diagnosis #rheumatology
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