19 results
diagnosis hematology anemia management signs symptoms algorithm blood causes classification erythematosus lupus product reactions sle systemic vasculitis agglutinin arthritis autoantibodies
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... malignancy, autoimmune disease ... HTN) • Recent travel ... /Fevers, DAT (-) ... #Anemia #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... bartonella (oroya fever ... #Anemia #Differential ... Algorithm #workup #hematology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... falls (like a wave ... Brucellosis Faget's Sign ... with profound hemolysis ... #Patterns #Differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... Lymphadenopathies 7% - Hemolytic ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... younger pts) Differential ... Symptoms: High fevers ... #hemolytic #anemia ... #hematology #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
long (in days) it takes ... Chronic kidney disease ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Approach to ECGs - Ischemia MI = Biomarkers + ECG or echo/angiogram findings Pathologic Q - 1/3 height
Equivalents / Don't Miss Signs ... bigger than QRS - deWinter ... T waves - starts ... triple vessel disease ... Interpretation #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... pain (20%) Renal disease ... normochromic nomocytic or haemolytic ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #rheumatology #
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... RBCs (stored at 4C ... diagnosis #management #hematology
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