25 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... lesions • Discoid lupus ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... , Fever, No muscle ... Diffuse muscle pain ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... /Symptoms Alopecia ... , Fever, Malar rash ... Erythematosus #SLE #Signs ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
involving small joints ... knees, shoulders Signs ... & Symptoms: • ... pain / swelling ... diagnosis #management #rheumatology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
• De Winter syndrome ... V2 • Wellens sign ... accompanied by chest pain ... • Wellens sign ... EKG #diagnosis #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #pain #Differential ... Diagnosis #MSK #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... thin smear • Signs ... Clinical findings of PAN ... values supporting hematologic