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differential nephrology algorithm causes management syndrome symptoms physicalexam signs workup pathophysiology treatment clinical table classification comparison pharmacology urology renal hyponatremia
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Between P2Y12 Inhibitors ... Oral P2Y12 inhibitors ... Switching P2Y12 inhibitors ... - Escalation ... Ticagrelor - De-escalation
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... of aldosterone inhibition ... • Calcineurin Inhibitors ... #differential #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... direct thrombin inhibitors ... Inhibitors: Non ... specific inhibitor ... Prolonged #Causes #diagnosis
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors A, Switching between oral agents in the acute/early phase.
Between Oral P2Y12 Inhibitors ... patients who are deescalating ... *Consider de-escalation ... De-escalation from ... .117.031164 #P2Y12 #Inhibitor
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Extrarenal Proton pump inhibitor ... Tyrosine kinase inhibitors ... - Calcineurin inhibitors ... #differential #diagnosis ... #nephrology #Causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Direct Xa inhibitors ... Specific inhibitors ... Specific inhibitors ... Inhibitors ... Prolonged #Causes #diagnosis
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
active metabolite inhibit ... Inhibition of this ... druginformation #nephrology
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis: https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext #Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Pathophysiology #Mechanism #Nephrology ... #SLGT2 #Inhibitors
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
- Differential Diagnosis ... Hypovolemia • RAAS inhibitor ... • Calcineurin inhibitor ... blockers - MCW Nephrology ... #Differential #Diagnosis
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
deficiency, or an inhibitor ... deficiencies and inhibitors ... Patient has a factor inhibitor ... Mixing #Study #diagnosis
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