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diagnosis hematology rheumatology algorithm classification deficiency extravascular hemolysis infections intravascular nutrition symptoms vasculitis aids anaplasma anemias bronchiectasis clues edema evaluation
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Diagnosis Algorithm Signs ... of anemia and hemolysis ... #Anemias #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... anemia • ... Extravascular #Differential ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... #differential # ... diagnosis #hematology ... #anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • Membrane defects ... #Anemia #Differential ... classification #hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... anaemia, ataxia ... , neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
scapularis • Infects ... within morulae Signs ... myalgias, shaking chills ... ), cough (30% cases ... immature forms) • Anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Vasculopathy #Purpura #Differential ... #nonpalpable #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
low, tests to detect ... result in severe anemia ... anemia Indirect ... WBC count and differential ... Diagnosis #Workup #Hematology
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... and coordination deficits ... Extraocular movement deficits ... #headache #signs ... #differential #
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
Edema (NCPE) - Differential ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... #differential #diagnosis
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