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endocrinology summary dpp4 medications sglt2 agonists comparison dosing glp1 indications management prescribing receptor renal titration weightgain weightloss
Effects on body weight of various classes of type-2 diabetes medications. - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... - Metformin - ... Loss + - SGLT-2 inhibitors ... weightgain #comparison #pharmacology
Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... gastrointestinal (GI) adverse effects ... Indications #Titration #Pharmacology ... #Diabetes #DM2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Pharmacology # ... Summary #DM2 #diabetes
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... Toxicities: • GI side effects ... #Pharmacology # ... Summary #DM2 #diabetes
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
drugs include side effects ... Side effects include ... combo product with metformin ... #Pharmacology # ... Medications #DM2
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... ) Common Side Effects ... • Euglycemic diabetic ... #Pharmacology # ... Summary #DM2 #diabetes
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... #Summary #DM2 # ... diabetes #endocrinology
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