17 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
leading to prolonged effects ... pharmacological effects ... by blocking the effects ... to block their effects ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... Summary #DM2 #diabetes
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #diabetes
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... to the incretin effect ... Common side effects ... #Pharmacology #Dosing ... #Diabetes #DM2
Side Effects of Atypical and Typical Antipsychotics - Comparison Table
Atypical antipsychotics: Risperidone, Quetiapine, Olanzapine, Amisulpride, Ziprasidone
Side Effects of ... Most adverse effects ... related adverse effects ... development of diabetes ... #Psychiatry #Pharmacology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Treatment for Diabetes ... gastrointestinal (GI) adverse effects ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Prescribing and Dosing ... • If Gl side effects ... #Prescribing #Dosing ... #CKD #pharmacology ... #algorithm #diabetes
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
treatment of type 2 diabetes ... point for side effects ... 2000 mg/day) and using ... #Metformin #Pharmacology ... #Mechanism #Diabetes
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Dose-dependent depressant effects ... Dose-dependent depressant effects ... with few amnestic effects ... of anxiolytic effects ... #comparison #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
15 g QD • Side Effects ... 8.4 g • Side Effects ... daily • Side Effects ... #medications #pharmacology ... #table #comparison